GERD (Gastroesophageal Reflux Disease) | Symptoms, Causes & Treatment

GERD (Gastroesophageal Reflux Disease) | Symptoms, Causes & Treatment
Upper GI & Digestive Disorders

GERD (Gastroesophageal Reflux Disease) | Symptoms, Causes & Treatment

SC
Written & Medically Reviewed By
Dr Samir Contractor · MS · FRCS (UK) · FMAS · FACS (USA)
Senior Consultant, Sterling Hospitals, Vadodara · Last reviewed: July 2026

GERD is a chronic condition in which stomach acid flows back into the food pipe frequently enough to cause symptoms or damage the esophageal lining. It is one of the most common GI conditions in India and affects millions of people across all age groups. Most cases are managed effectively with lifestyle changes and medication. A minority need surgical correction.

✦ Quick Answers

What is GERD? A chronic condition where stomach acid flows back into the food pipe more than twice a week, causing heartburn, regurgitation, and potentially damaging the esophageal lining.
Is GERD serious? GERD itself is manageable. Left untreated for years, it can cause esophagitis, stricture, and Barrett's esophagus - a precancerous change requiring surveillance.
What causes GERD? A weak or intermittently relaxing lower esophageal sphincter (anti-reflux valve), often worsened by obesity, late meals, fatty food, smoking, hiatal hernia, and pregnancy.
When is surgery needed? When confirmed GERD with hiatal hernia does not respond adequately to properly taken PPI therapy. Surgery requires pre-operative endoscopy, pH study, and manometry.
What is Barrett's esophagus? A precancerous cellular change in the lower food pipe from long-term acid exposure. Requires regular endoscopic surveillance. Found during endoscopy.
Tests needed? Endoscopy when persistent or with red flags. H. pylori testing. 24-hour pH monitoring when surgery is planned or diagnosis is uncertain.

GERD is not simply occasional heartburn. It is a chronic disease in which the mechanism protecting the food pipe from stomach acid is persistently or frequently failing. The lower esophageal sphincter - the muscular valve between the food pipe and stomach - does not close properly, allowing acid and sometimes food to rise into the esophagus regularly.

In India, GERD is extremely prevalent. Dietary habits, rising obesity rates, and the widespread practice of eating late and sleeping soon after are major drivers. Many patients manage with antacids for years before receiving a proper diagnosis. This page covers what GERD actually is, how severe it can be, and what treatment is appropriate at each stage.


What Is GERD?

GERD (gastroesophageal reflux disease) is diagnosed when acid reflux occurs frequently enough - more than twice a week - or causes measurable damage to the food pipe. The medical definition distinguishes GERD from occasional acid reflux, which is a common and usually benign event.

GERD has two main forms:

  • Erosive GERD (ERD) - acid reflux has caused visible inflammation, erosions, or ulcers of the esophageal lining (esophagitis). This is seen on endoscopy and graded A-D by severity (Los Angeles classification)
  • Non-erosive GERD (NERD) - symptoms of GERD are present but the esophageal lining appears normal on endoscopy. This is the more common form. Diagnosis is confirmed by 24-hour pH monitoring.

Los Angeles Classification of Esophagitis

Grade Finding on Endoscopy Clinical Significance
A One or more mucosal breaks ≤5 mm, not crossing mucosal folds Mild - usually responds well to PPI therapy
B One or more mucosal breaks >5 mm, not crossing mucosal folds Moderate - PPI therapy, lifestyle change
C Mucosal breaks crossing at least two mucosal folds but covering <75% of circumference Significant - higher-dose PPI, consider surgery evaluation
D Mucosal breaks covering ≥75% of esophageal circumference Severe - high complication risk; surgical evaluation often indicated

Symptoms of GERD

Typical (esophageal) symptoms

  • Heartburn - burning sensation in the chest or throat, worst after meals and at night
  • Regurgitation - sour or bitter material rising into the throat or mouth
  • Chest pain - from acid-induced esophageal spasm; must be distinguished from cardiac pain
  • Difficulty swallowing - when complications (stricture, severe esophagitis) have developed

Atypical (extra-esophageal) symptoms

  • Chronic dry cough - particularly at night or early morning; from acid reaching the airways (LPR)
  • Hoarseness of voice - from acid affecting the vocal cords
  • Sore throat or globus sensation (lump in throat)
  • Worsening or refractory asthma
  • Dental erosion - acid repeatedly reaching the mouth
  • Chronic sinusitis in some patients

What Causes GERD?

GERD results from a failure of the anti-reflux mechanism. Contributing factors include:

  • Weak or transiently relaxing lower esophageal sphincter (LES) - the primary mechanism; allows acid to escape upward between swallows
  • Hiatal hernia - the stomach slides into the chest cavity, displacing the LES and disrupting the anti-reflux barrier
  • Obesity - central abdominal fat increases intra-abdominal pressure, chronically overloading the LES
  • Late-night eating and large meals - a full stomach at bedtime is the most powerful precipitating factor for GERD in Indian patients
  • Dietary triggers - fatty and fried food, spicy food, coffee, tea, alcohol, carbonated drinks - all reduce LES pressure or increase acid production
  • Smoking - nicotine directly weakens the LES
  • Pregnancy - hormonal relaxation of the LES combined with uterine pressure
  • NSAIDs and certain medications - aspirin, calcium channel blockers, nitrates, and some antidepressants weaken the LES

Red Flags in GERD - When to Escalate

Urgent endoscopy is needed if GERD is associated with:

  • Difficulty swallowing - possible stricture or cancer development
  • Unintended weight loss
  • Blood in vomit or black stool - upper GI bleeding
  • Symptoms present for 5+ years without a single endoscopy - Barrett's risk
  • New-onset symptoms in a person above 45
  • Progressive worsening despite adequate PPI therapy

Who Is at Higher Risk?

  • Overweight or obese individuals - particularly central obesity, extremely common in urban India
  • Those who eat late, eat large meals, or sleep within 2 hours of eating
  • People with a confirmed hiatal hernia
  • Pregnant women - particularly in the second and third trimester
  • Smokers and regular alcohol users
  • People on NSAIDs, aspirin, or certain antihypertensive medications
  • Post-bariatric surgery patients (sleeve gastrectomy) - incidence of new or worsened GERD is high

How GERD Is Evaluated

The diagnosis of GERD can be made clinically in most patients with typical symptoms (heartburn + regurgitation) and a positive response to PPI therapy. Investigation is added when:

  • Symptoms are atypical or the diagnosis is uncertain
  • Red-flag features are present
  • Symptoms persist despite adequate PPI therapy
  • Surgery is being considered
  • Patient has had symptoms for 5+ years (Barrett's surveillance)

Tests That May Be Needed

Not every GERD patient needs every test. Investigations are guided by symptom severity, response to treatment, and red-flag features.

Upper GI Endoscopy

Direct visualisation of the food pipe, stomach, and duodenum. Identifies esophagitis grade (A-D), hiatal hernia, Barrett's esophagus, peptic ulcer, and malignancy. Biopsies confirm H. pylori and Barrett's histology.

24-hour pH monitoring / pH impedance

The gold standard for confirming GERD. Measures acid exposure in the food pipe over 24 hours and correlates with symptoms. Essential before surgical planning. pH impedance also detects non-acid reflux.

Esophageal manometry

Measures LES pressure and esophageal peristalsis. Mandatory before anti-reflux surgery to ensure adequate esophageal motility and to exclude achalasia or other motility disorders.

H. pylori testing

Urea breath test or stool antigen. H. pylori eradication reduces upper GI symptom burden and is part of comprehensive GERD management in India.

Treatment of GERD

Indian Dietary Guidance for GERD

  • Most impactful: Dinner no later than 7-7:30 PM; sleep no earlier than 10-10:30 PM - this single 2-3 hour gap reduces nighttime symptoms dramatically
  • Best choices: Soft khichdi, plain dal, soft roti with light sabzi, curd (at lunch, not dinner), banana, chaas, steamed vegetables
  • Reduce significantly: Ghee-heavy curries, oily preparations, deep-fried snacks, very spicy food, large thali portions at night
  • Head elevation: A wedge pillow or raising the head of the bed by 15-20 cm - not just extra pillows under the head - reduces nocturnal acid exposure measurably

When Is Surgery the Right Choice?

Laparoscopic fundoplication (most commonly Nissen or Toupet) wraps the upper stomach around the lower food pipe to reinforce the anti-reflux valve. It provides durable long-term symptom control in well-selected patients.

Indications:

  • Confirmed GERD on objective testing (endoscopy + pH study)
  • Significant hiatal hernia confirmed on endoscopy
  • Inadequate symptom control on optimised, correctly taken PPI therapy
  • Patient preference for surgical correction over lifelong medication
  • Aspiration from severe regurgitation - a safety indication
  • Obese patient where bariatric surgery is also being considered - gastric bypass preferred over sleeve (sleeve worsens GERD)

Pre-operative workup:

  • Upper GI endoscopy - confirms diagnosis, grades severity
  • 24-hour pH monitoring - objectively documents acid exposure
  • Esophageal manometry - confirms adequate peristalsis before fundoplication

What Happens If GERD Is Left Untreated?

  • Progressive esophagitis - grade A to D over years
  • Esophageal ulceration - bleeding, pain
  • Esophageal stricture - progressive narrowing causing increasing difficulty swallowing
  • Barrett's esophagus - precancerous change; small but real cancer risk requiring surveillance
  • Esophageal adenocarcinoma - the most serious long-term complication of chronic, untreated GERD
  • Aspiration pneumonia - from nighttime regurgitation
  • Dental erosion and chronic ENT symptoms - from acid reaching the mouth and airways

Recovery and What Patients Can Expect

  • With lifestyle + PPI: Most patients achieve good symptom control within 2-4 weeks. Full esophagitis healing at 8 weeks. Many patients can step down to maintenance dosing or stop altogether with sustained lifestyle changes.
  • After laparoscopic fundoplication: Hospital stay 1-2 days. Soft diet for 3-4 weeks. Return to normal activity in 1 week. Most patients stop or significantly reduce PPIs within 3 months. Long-term symptom control is excellent in well-selected patients.

Frequently Asked Questions

Acid reflux is the event - stomach acid flowing backward. GERD is the chronic disease - when acid reflux occurs frequently enough (more than twice a week) or causes complications. Think of acid reflux as the symptom and GERD as the established diagnosis when it is persistent and measurable.

GERD itself does not directly cause cancer. However, long-term untreated GERD can lead to Barrett's esophagus - a precancerous change in the esophageal lining. Barrett's esophagus carries a small but real increased risk of esophageal adenocarcinoma. This is why patients with long-standing GERD should have an endoscopy and, if Barrett's is found, a surveillance programme.

Yes - for the vast majority of patients, long-term PPI use is safe. The risks (marginal B12 and magnesium absorption effects, slightly increased susceptibility to certain gut infections) are low and well-characterised. The benefits of treating established GERD outweigh these risks. Long-term use should be supervised with periodic review by a doctor.

Sleeve gastrectomy significantly increases the risk of new or worsened GERD. The sleeve removes the gastric fundus (which normally stores food and has a low-pressure capacity), creates a narrow high-pressure tube, and can damage the angle of His - all factors that promote reflux. Patients considering bariatric surgery with existing GERD should discuss gastric bypass (which often improves GERD) as an alternative to sleeve gastrectomy.

Barrett's esophagus is a change in the cells lining the lower food pipe from normal squamous cells to intestinal-type columnar cells - caused by chronic acid exposure. Most patients with Barrett's do not develop cancer. Non-dysplastic Barrett's is typically surveyed every 3-5 years by endoscopy and biopsy. Low-grade dysplasia every 6-12 months. High-grade dysplasia requires endoscopic treatment (ESD or ablation) or surgical management. PPI therapy is continued in all patients with Barrett's.

Yes - up to 50-70% of GERD patients have a normal-appearing food pipe on endoscopy. This is called non-erosive reflux disease (NERD). A normal endoscopy does not mean you do not have GERD - it means acid reflux has not caused visible damage yet. 24-hour pH monitoring confirms whether pathological acid reflux is occurring and helps guide treatment decisions.

This depends on the severity and underlying cause. For mild GERD responding to lifestyle changes - medication may be stopped after an initial course. For moderate-severe esophagitis or Barrett's - long-term maintenance PPI therapy is recommended. For patients with a confirmed hiatal hernia - surgery may be preferable to indefinite medication. Your doctor will advise based on your endoscopy findings and symptoms response.

Weight loss significantly reduces GERD symptoms and, in some patients, leads to complete resolution. Central abdominal obesity directly increases intra-abdominal pressure and LES dysfunction. A 5-10% reduction in body weight measurably reduces reflux frequency and severity. In obese patients with GERD, weight management - through lifestyle or bariatric surgery - is the most durable long-term intervention available.

When acid reaches the upper food pipe and larynx, it triggers a protective cough reflex and causes inflammation of the vocal cords - producing hoarseness. This is called laryngopharyngeal reflux (LPR). LPR often occurs without typical heartburn, making it difficult to recognise. It responds to twice-daily PPI therapy combined with strict dietary and positional measures. Response is slower than with typical GERD - often 2-3 months.

Laparoscopic Nissen fundoplication wraps the stomach around the lower esophagus to recreate the valve. LINX is a magnetic sphincter augmentation device - a ring of magnets placed around the lower esophagus that strengthens the valve while still allowing food to pass. Both are laparoscopic procedures. Fundoplication is more widely available in India. LINX is available at specialist centres and has certain advantages in patients with concerns about swallowing difficulty post-fundoplication.

GERD in India - What Is Relevant for You

India-specific context for GERD

  • GERD prevalence in urban India is estimated at 15-20% - making it one of the most common GI conditions in the country
  • The Indian eating pattern - large oily dinner eaten late, followed by sleep - is one of the most powerful GERD triggers in the world and is rarely modified without specific dietary counselling
  • Barrett's esophagus surveillance is inadequately practised in India - many patients with long-standing GERD have never had an endoscopy to identify it
  • Post-sleeve gastrectomy GERD is an emerging major problem in India's growing bariatric surgical population - all sleeve patients with reflux should be evaluated
  • H. pylori coexists with GERD in a high proportion of Indian patients - eradication is part of comprehensive GERD management here

Seek Care in Vadodara

For persistent GERD, suspected Barrett's esophagus, or GERD surgery consideration - consult Dr Samir Contractor at Sterling Hospital, Vadodara. Endoscopy, pH monitoring, manometry, and laparoscopic surgery are all available in one centre.

Desi Patient Questions

GERD ane simple acidity ma shu farq chhe?

Simple acidity occasional hoy chhe - heavy meal pachhi. GERD chronic chhe - week ma 2+ vaar hoy, raat ne disturb kare, medicine thi manage thatu hoy. GERD ma long-term esophagus damage thay shake chhe - evaluation ane proper treatment zaruri chhe.

Barrett's esophagus shu chhe ane shu mane cancer thay?

Barrett's esophagus = food pipe ni cells change thay chhe acid thi. Cancer nu risk slightly higher chhe - but majority patients ne cancer nathi thato. Surveillance endoscopy every 3-5 years recommended chhe. PPI therapy continue karo. Early detection thi, if anything develops, treatment excellent chhe.

GERD surgery karvana fear chhe - shu medicine thi lifelong nahi chale?

Bahu patients ma medicine + lifestyle thi long-term chale chhe. Surgery specifically recommended thay jyaré: hiatal hernia confirmed hoy, medicine proper leva pachi pan nathi kaam kartu, ya long-term medicine avoid karvani patient ki ichha hoy. Endoscopy + pH study - first. Surgery decision after workup.

Sleeve surgery lidha pachhi GERD vadhyo - shu karvu?

Post-sleeve GERD serious concern chhe. PPI start karo ane bariatric team ne inform karo. Severe cases ma gastric bypass conversion evaluate thay chhe - e GERD improve kare chhe. Dismiss na karo - proper follow-up important chhe.

Article Reviewed by: Dr. Samir Contractor, Senior Consultant Laparoscopic, Anorectal & Bariatric Surgeon, MS, FRCS(UK), FMAS, FACS(USA), PN Certified exercise and Nutrition Coach (Canada)
Clinical expertise: Anorectal surgery, advanced laparoscopy, bariatric & metabolic surgery. Medically Supervised Weight loss program
Experience: 25+ years of Clinical experience.
Last medically reviewed: April 2026
Editorial policy: Content on drsamircontractor.com is written and reviewed by a practising surgeon. Each page is updated whenever clinical practice guidelines change.
Medical Disclaimer: This page is for educational purposes only and does not replace a face-to-face consultation with a qualified medical professional. The information provided is based on general clinical principles and may not apply to every individual case. Do not self-diagnose or self-treat based on this content. Dr. Samir Contractor and Sterling Hospital, Vadodara, are not responsible for decisions made based solely on this information.